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基于光纤表面等离子体共振传感技术的电压检测研究

需求编号:TK2016101000002 需求类型:技术 行业分类:网络通讯(通讯设备)
面向区域:中国 开始时间:2016年10月11日 结束时间:2017年10月11日
中标模式:多人中标 保密需求:
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关键字: 光纤

需求描述

[需求项目名称] 基于光纤表面等离子体共振传感技术的电压检测研究[需求单位名称] 中国科学院重庆绿色智能技术研究院[需求单位信息] 1、单位概况(200字以内) 中国科学院重庆绿色智能技术研究院是中国科学院、国务院三峡办、重庆市人民政府三方共建的中国科学院直属科研机构,在电子信息、先进制造、生态环境三个领域进行布局,以重庆及西部区域经济社会发展重大需求为牵引,以绿色化、智能化、产品化为方向,面向世界科技前沿,重点开展产业关键核心技术与前沿技术创新、技术集成创新、工程化研发和科技成果转移转化工作,与技术创新体系和区域创新体系紧密结合,提升区域创新发展能力。2、国际合作现状(100字以内) 采用光纤表面等离子体共振传感技术能有效延长神经细胞电压可检测时间,降低植入式检测对细胞的创伤,有效提高细胞电压的检测灵敏度。英国诺丁汉大学在利用光纤表面等离子体共振传感技术监测细胞活动领域有着多年的研究和技术经验积累,通过合作研发有助于项目的开展和双方的技术进步。  [技术需求概要] 1、需求项目的重要性和必要性,与全市重要工程和重点产业的关联程度(300字以内) 目前,活体神经细胞的监测多采用微电极和电压敏感荧光染料。它们的一个共同缺点就是不能实现神经细胞活动的长期记录。本项目拟采用光纤表面等离子体共振技术监测神经细胞电压,通过系统地研究光纤表面等离子体共振传感探针与电压反应的机理和响应规律,设计并制作面向长期监测神经细胞电压的具有高灵敏度的光纤表面等离子体共振传感探针及设备,实现运用该种传感技术对活体神经细胞电位的原位检测。 结合我市确立的智能医疗检测器械的发展方向,面向监测神经细胞电压使用的光纤表面等离子体共振传感技术将有助于提高我市医疗检测器械的技术水平,引领神经细胞检测水平的提升,为科研院所和医学院提供具有前沿技术水平的仪器装备。  2、需求项目的技术突破及创新点(150字以内) 合作的内容和目标:1. 光纤探针制作技术:具有不同形状的光纤传感探针;互派人员学习访问,交流项目开发知识。 2. 细胞原位监测技术:合理开发和运用光纤传感探针监测技术及数据分析技术,实现传感探针对神经细胞的创伤最小化。交流神经细胞检测技术。  [期望的合作方式]R技术引进 R委托开发 R成立联合研发中心或实验室   □人才引进 R召开国际学术会议                     [联系人]黄昱        [电话] 手机:13637856627 [电子邮箱]:huangyu@cigit.ac.cn[传真]:(023)63063989                                                                        [Requested Project Name] Investigation of voltage sensing by fiber optic surface plasmon resonance sensor  [Requester] Chongqing Institute of Green and Intelligent Technology,Chinese Academy of Science  [Basic Information] 1. General Information of Requester The CAS Chongqing Institute of Green and Intelligent Technology (CIGIT) is a scientific research institution according to a cooperation agreement by the CAS, the Executive Office of the State Council Three Gorges Project Construction Committee and the Chongqing municipal government. CIGIT is established in southwest China’s Chongqing Municipality to promote progress and innovation in areas of electronic information, intelligent manufacturing and ecological environment. The Institute of Electronic Information will be aimed to crack down key technologies in intelligence, intelligent control and massive information processing, and in the meanwhile, try best to make electronic information products energy-saving and environmental friendly. Its research directions include green information system, services for cultural and creative industry, cloud computing and automotive electronics. The Institute of Intelligent Manufacturing will be engaged in such areas like intelligent industrial design, green manufacturing technology, agile manufacturing technology and intellectual instruments and smart sensors. As for the Institute of Environmental Engineering, its focus will be set on the large-scale reservoirs located in areas with a complex man-land relation and environmental construction and protection of Three Gorges reservoir area. A system of prevention technology, equipment and management of environmental protection will be developed to help solve the problems popping up in the increasingly speeding-up industrialization and urbanization in Chongqing    2. International Cooperation Status The neural action potential recording time is able to be prolonged and the hurt to neuro during detection could be minimized by using fiber optic surface plasmon resonance sensor. The most advantage of fiber optic SPR sensor is that the voltage sensitivity can be improved significantly. The University of Nottingham (UK) has a long history to develop the state-of-art surface plasmon resonance technology to record neural activity. This cooperation between CIGIT and the University of Nottingham is believed to enhance the mutual R&D ability and promote the SPR technology in the field of biological application.  [Technical Requirements Summary] 1. Importance and necessity of requested project, and relations with key projects and industries of Chongqing City. Traditional neuroscience methodology in recording neural activity is ranging from microelectrode arrays to voltage-sensitive fluorescence dyes. However, fail to realization of chronic recording is their common drawback. This project is to explore the potential application of surface plasmon resonance (SPR) fiber optic sensor in vivo recording of neural activity. The mechanism of optical response of SPR fiber optic sensor to voltage will be investigated systematically. The development of high voltage sensitive SPR fiber optic probe and its associated measurement system will be carried out. A novel and reliable fiber optic probe will be utilized for neural recording in vivo. The spirit of this project belongs to one categories of Chongqing scientific development blueprint, which is to develop intelligent medical detection device. The development of voltage-sensitive fiber optic SPR sensor will improve the core technology of biological detection, and benefit research strength of R&D institutes.  2. Technology breakthroughs and innovations of requested project The content and goals of cooperation: 1.     Fabrication of fiber optic SPR sensor. Development of various sized and shaped fiber optic sensor designed for the voltage detection. Exchange of learning and participation in project development. 2.     Neural recording in vivo: Development of skill suitable for neural action potential recording in vivo by using fiber optic SPR sensor and data analysis technology. The aim is to minimize the hurt to neuro caused by fiber optic sensor invasion. The exchange of neural recording technology in vivo by using fiber optic sensor. [Expected Ways of Cooperation] Technology ImportThird Party R&D Joint Research Center/Lab □Talent Introduction International Conference                    [Contact]:Huang Yu            [Phone] Office        Cell86-13637856627  [E-mail]huangyu@cigit.ac.cn              [Fax] 86-023-63063989  



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